Confusion, Seizures, & Vision Loss

A 35-year-old with IgA nephropathy develops confusion, seizures, and Blurry Vision after starting cyclosporine. Explore this critical neurological syndrome.

Posterior reversible encephalopathy syndrome


A 35-year-old man with IgA nephropathy presented with confusion, blurry vision, and seizures. Two weeks before presentation, he had started receiving cyclosporine. Physical examination was notable for a blood pressure of 160/80 mm Hg, drowsiness, and decreased visual acuity. A fundoscopic examinations was normal. T2-weighted magnetic resonance imaging (MRI) with fluid-attenuated inversion recovery sequencing of the head was performed. What is the most likely diagnosis?

What is the most likely diagnosis?

Acute demyelinating encephalomyelitis
Methanol ingestion
Multifocal ischemic infarcts
Posterior reversible encephalopathy syndrome
West Nile virus encephalitis

Cyclosporine, Hypertension, Neurology, Posterior reversible encephalopathy syndrome, Seizures

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