The Ominous Umbilical Nodule

A 73-year-old woman presents with a painful, enlarging umbilical nodule. Explore the Differential Diagnosis and workup for this concerning physical finding.

Sister Mary Joseph's nodule


A 73-year-old woman presented to the emergency department with a painful umbilical nodule that had been enlarging over the past 4 months. Physical examination revealed a painful and firm erythematous umbilical nodule measuring 2 cm in its largest diameter. What is the likely diagnosis?

What is the most likely diagnosis?

Keloid
Umbilical hernia
Pyoderma gangrenosum
Pyogenic granuloma
Sister Mary Joseph’s nodule

Metastasis, Oncology, Ovarian Cancer, Sister Mary Joseph’s nodule, Umbilical Nodule

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