A preterm baby girl develops vesicular skin lesions immediately after birth. Explore the Differential Diagnosis for a newborn rash and key diagnostic steps.
A baby girl was noted to have vesicular skin lesions immediately after spontaneous vaginal delivery at 32 weeks’ gestation. Her 37-year-old mother had premature rupture of membranes 12 days before the delivery. On physical examination, clusters of vesicles were seen on the infant’s torso (left), periumbilical region (right), and pharyngeal, nasal, and conjunctival mucosa. No lesions were seen on the mother’s genitals or the placenta. What is the most likely diagnosis?
What is the most likely diagnosis?
Acyclovir, Congenital infection, HSV-1, Neonatal herpes simplex virus, Vesicular rash
