A 30-year-old man develops a rash, fever, and facial edema after taking antibiotics. Explore this case of severe drug hypersensitivity with Eosinophilia.
A 30-year-old man was admitted to the hospital with 2 weeks of rash and fever that had started one month after taking a course of trimethoprim–sulfamethoxazole for the treatment of folliculitis. Physical examination was notable for fever, a diffuse morbilliform rash, submandibular lymphadenopathy, and facial erythema with periorbital sparing. Four days after admission, facial edema developed. Labs showed elevated absolute eosinophils and aminotransferase levels. What’s the most likely diagnosis?
What is the most likely diagnosis?
DRESS syndrome, Drug reaction with eosinophilia and systemic symptoms, Eosinophilia, Severe cutaneous adverse reaction, Sulfonamides
