When Cysts Crowd the Liver

A 51-year-old woman presents with worsening Abdominal pain. Exam and imaging reveal an enlarged liver filled with cysts. What is the underlying cause?

Autosomal dominant polycystic kidney disease


A 51-year-old woman presented to the primary care clinic with mild worsening of chronic abdominal pain. On physical examination, the liver was enlarged. Magnetic resonance cholangiopancreatography revealed a markedly enlarged liver with numerous cystic structures (a three-dimensional maximum-intensity-projection reconstruction is shown in the figure). What is the most likely underlying diagnosis?

What is the most likely diagnosis?

Alpha1-antitrypsin deficiency
Amebiasis
Autosomal dominant polycystic kidney disease
Hepatocellular adenomas
Tuberous sclerosis

Abdominal pain, Autosomal dominant polycystic kidney disease, Genetics, Hepatomegaly, Polycystic liver disease

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