When Palms and Soles Turn Yellow

A patient presents with yellow discoloration of the palms and soles. Explore the Differential Diagnosis, including carotenemia, liver disease, and metabolic disorders.

Diabetes mellitus


This patient presented with discoloration of his palms and soles. He reported a normal diet and had normal serum creatinine, thyroxine, and bilirubin concentrations. What is the diagnosis?

What is the most likely diagnosis?

Diabetes mellitus
Vitamin B12 deficiency
Amiodarone exposure
Hyperlipidemia type III
Syphilis

Carotenemia, Diabetes Mellitus, Differential Diagnosis, Endocrinology, Xanthoderma

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