When Raising Arms Causes Facial Flushing

Explore the case of a 77-year-old man whose enlarged thyroid leads to facial congestion upon raising his arms, a classic sign of thoracic inlet obstruction.

Pemberton's sign


A 77-year-old man was referred to the endocrinology clinic for evaluation of subclinical hyperthyroidism. Physical examination revealed an enlarged thyroid with no palpable nodules or cervical lymphadenopathy. When the patient raised both arms, he developed reversible facial congestion. What is the name of this sign?

What is the most likely diagnosis?

Grave’s sign
Hashimoto’s sign
Pemberton’s sign
Flemingo’s flush sign
Lighthouse sign

Hyperthyroidism, Pemberton’s sign, Superior Vena Cava Syndrome, Thoracic Inlet Obstruction, Thyroid Goiter

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